Dual mechanism design to enhance bone formation by overexpressed SDF-1 ADSCs in magnesium doped calcium phosphate scaffolds
Abstract
SDF-1/CXCR4 axis plays a critical role in the mobilization and regeneration of host-derived cells. Little is known around the role of SDF-1 gene on bone regeneration. This study was conceptualized to create a 2-in-1 strategy by identifying potential role of SDF-1 on promoting endogenous osteoblast migration and synergizing with magnesium doped calcium phosphate scaffold (MCPC) on osteogenic differentiation. ADSCs were transfected with...
Paper Details
Title
Dual mechanism design to enhance bone formation by overexpressed SDF-1 ADSCs in magnesium doped calcium phosphate scaffolds
Published Date
Oct 1, 2021
Journal
Volume
208
Pages
109884 - 109884
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