Teaching tolerance: Diverse cellular interactions enable healthy maturation
Abstract
The fetal immune system is distinguishable from the adult immune system by a higher degree of tolerance to foreign antigens. This tolerance is important for fetal development within the ‘foreign’ maternal environment, and during birth when barrier surfaces are first colonized by microbiota. Immune responses against the wave of newly colonizing microbiota would cause massive damage to barrier tissues, so neonates need suppressed immune responses...
Paper Details
Title
Teaching tolerance: Diverse cellular interactions enable healthy maturation
Published Date
Jun 16, 2021
Journal
Volume
163
Issue
3
Pages
237 - 238
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Notes
History