A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts
Abstract
Plasma lipids are known heritable risk factors for cardiovascular disease, but increasing evidence also supports shared genetics with diseases of other organ systems. We devised a comprehensive three-phase framework to identify new lipid-associated genes and study the relationships among lipids, genotypes, gene expression and hundreds of complex human diseases from the Electronic Medical Records and Genomics (347 traits) and the UK Biobank (549...
Paper Details
Title
A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts
Published Date
Jun 17, 2021
Journal
Volume
53
Issue
7
Pages
972 - 981
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