DOP51 De-escalation of biological therapy in Inflammatory Bowel Disease patients following prior escalation

Background There are limited data available on de-escalation of biological therapy after prior escalation in inflammatory bowel disease (IBD) patients. The aim of this study was to assess the frequency and success rate of de-escalation of biological therapy in IBD patients after prior dose escalation and evaluate which measures are used prior to de-escalation. Methods This multicentre, prospective, cohort study enrolled IBD patients treated with...