Molecular determinants of disease severity in urinary tract infection

Volume: 18, Issue: 8, Pages: 468 - 486
Published: Jun 15, 2021
Abstract
The most common and lethal bacterial pathogens have co-evolved with the host. Pathogens are the aggressors, and the host immune system is responsible for the defence. However, immune responses can also become destructive, and excessive innate immune activation is a major cause of infection-associated morbidity, exemplified by symptomatic urinary tract infections (UTIs), which are caused, in part, by excessive innate immune activation. Severe...
Paper Details
Title
Molecular determinants of disease severity in urinary tract infection
Published Date
Jun 15, 2021
Volume
18
Issue
8
Pages
468 - 486
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