Scalable Production of Lipid Nanoparticles Containing Amphotericin B
Abstract
Lipid-based formulations have been developed to improve stability profiles, tolerability, and toxicity profiles of small molecule drugs. However, manufacture of such formulations involving lipophilic compounds can be labor-intensive and difficult to scale because of solubility and solvent compatibility issues. We have developed a rapid and scalable approach using rapid-mixing techniques to generate homogeneous lipid nanoparticle (LNP)...
Paper Details
Title
Scalable Production of Lipid Nanoparticles Containing Amphotericin B
Published Date
Jun 8, 2021
Journal
Volume
37
Issue
24
Pages
7312 - 7319
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