Radiation-induced YAP activation confers glioma radioresistance via promoting FGF2 transcription and DNA damage repair

Volume: 40, Issue: 27, Pages: 4580 - 4591
Published: Jun 14, 2021
Abstract
Although radiotherapy is a well-known effective non-surgical treatment for malignant gliomas, the therapeutic efficacy is severely limited due to the radioresistance of tumor cells. Previously, we demonstrated that Yes-associated protein (YAP) promotes glioma malignant progression. However, whether YAP plays a role in radioresistance and its potential value in cancer treatment are still unclear. In this study, we found that high YAP expression...
Paper Details
Title
Radiation-induced YAP activation confers glioma radioresistance via promoting FGF2 transcription and DNA damage repair
Published Date
Jun 14, 2021
Journal
Volume
40
Issue
27
Pages
4580 - 4591
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