New short cationic antibacterial peptides. Synthesis, biological activity and mechanism of action

Volume: 1863, Issue: 10, Pages: 183665 - 183665
Published: Oct 1, 2021
Abstract
We report a theoretical and experimental study on a new series of small-sized antibacterial peptides. Synthesis and bioassays for these peptides are reported here. In addition, we evaluated different physicochemical parameters that modulate antimicrobial activity (charge, secondary structure, amphipathicity, hydrophobicity and polarity). We also performed molecular dynamic simulations to assess the interaction between these peptides and their...
Paper Details
Title
New short cationic antibacterial peptides. Synthesis, biological activity and mechanism of action
Published Date
Oct 1, 2021
Volume
1863
Issue
10
Pages
183665 - 183665
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