Squalene nanoemulsion reinforces mucosal and immunological fingerprints following intravaginal delivery
Abstract
This study describes the assessment of mucosal adjuvant activity of a squalene-based nanoemulsion (SQ@NE) following intravaginal delivery in mice. After immunization, a high level of recruitment of CD11b/c+ granulocytes and F4/80+ macrophages was observed in the vaginal mucosal tissues of the mice immunized with a model protein ovalbumin (OVA) formulated with SQ@NE, and then downstream regulated the expression of MHC II and costimulatory...
Paper Details
Title
Squalene nanoemulsion reinforces mucosal and immunological fingerprints following intravaginal delivery
Published Date
Sep 1, 2021
Volume
141
Pages
111799 - 111799
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