STING pathway expression in low‐grade serous carcinoma of the ovary: an unexpected therapeutic opportunity?
Abstract
Ovarian carcinoma histotypes are distinct diseases with variable clinical outcomes and response to treatment. There is a need for new subtype-specific treatment modalities, especially for women with widespread and chemo-resistant disease. Stimulator of interferon genes (STING) is a part of the cGAS-STING pathway that mediates innate immune defence against infectious DNA-containing pathogens and also detects tumour-derived DNA and generates...
Paper Details
Title
Published Date
Jun 17, 2021
Journal
Volume
7
Issue
6
Pages
548 - 555
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