Three labdane diterpenoids from the aerial parts of Leonurus japonicus
Abstract
Three undescribed labdane diterpenoids, 15,16-epoxy-13,15-dihydroxylabd-8-ene-7-one (1), 15,16-epoxy-13-hydroxy-15-methoxylabd-8-ene-7-one (2) and 15-hydroxyleoheteronin B (3), along with eight known compounds, were isolated from an ethyl acetate extract of Leonurus japonicus. Their structures were elucidated using spectroscopic methods, mainly 1-D and 2-D NMR. Compound 1 showed the strongest cytotoxic activity against MCF-7 cells with IC50...
Paper Details
Title
Three labdane diterpenoids from the aerial parts of Leonurus japonicus
Published Date
Aug 1, 2021
Journal
Volume
44
Pages
82 - 86
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