Roles for growth factors and mutations in metastatic dissemination

Volume: 49, Issue: 3, Pages: 1409 - 1423
Published: Jun 8, 2021
Abstract
Cancer is initiated largely by specific cohorts of genetic aberrations, which are generated by mutagens and often mimic active growth factor receptors, or downstream effectors. Once initiated cells outgrow and attract blood vessels, a multi-step process, called metastasis, disseminates cancer cells primarily through vascular routes. The major steps of the metastatic cascade comprise intravasation into blood vessels, circulation as single or...
Paper Details
Title
Roles for growth factors and mutations in metastatic dissemination
Published Date
Jun 8, 2021
Volume
49
Issue
3
Pages
1409 - 1423
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