Urodynamic Characterization of Aged Ossabaw Miniature Pigs Mimics Human Detrusor Underactivity

Detrusor underactivity (DU) and its clinical correlate, underactive bladder (UAB), are common urologic conditions experienced by up to 20 million Americans, however, its pathophysiology is poorly understood and treatment is limited. This highlights the need for a high fidelity animal model that has similar bladder characteristics that will allow direct testing of new treatment modalities. Building on our previous study in metabolic syndrome pigs...