Increased visceral sensitivity, elevated anxiety, and depression levels in patients with functional esophageal disorders and non‐erosive reflux disease

Little is known about possible underlying psychological abnormalities and physiology of reflux hypersensitivity (RH) as defined in the recent Rome IV classification. We aimed to assess markers of psychological comorbidity as well as gastro-esophageal reflux measurements in RH patients compared to controls and also in patients with functional heartburn (FH) and non-erosive reflux disease (NERD) versus controls.Data of 304 patients visiting our...