Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy

Volume: 64, Issue: 12, Pages: 7963 - 7990
Published: Jun 8, 2021
Abstract
Microtubules play a crucial role in multiple cellular functions including mitosis, cell signaling, and organelle trafficking, which makes the microtubule an important target for cancer therapy. Despite the great successes of microtubule-targeting agents in the clinic, the development of drug resistance and dose-limiting toxicity restrict their clinical efficacy. In recent years, multitarget therapy has been considered an effective strategy to...
Paper Details
Title
Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy
Published Date
Jun 8, 2021
Volume
64
Issue
12
Pages
7963 - 7990
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