Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients
Abstract
Down syndrome (DS) patients prematurely show clinical manifestations usually associated with aging. Their immune system declines earlier than healthy individuals, leading to increased susceptibility to infections and higher incidence of autoimmune phenomena. Clinical features of accelerated aging indicate that trisomy 21 increases the biological age of tissues. Based on previous studies suggesting immune senescence in DS, we hypothesized that...
Paper Details
Title
Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients
Published Date
Jun 1, 2021
Journal
Volume
12
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