Local immune microenvironment of skin may play an important role in the development of pretibial myxedema
Abstract
Pretibial myxedema (PTM), characterized by the accumulation of glycosaminoglycans in dermis is an autoimmune skin disorder, which is almost always associated with Graves' disease (GD). Although fibroblast stimulated by thyroid-stimulating hormone receptor (TSHR) antibody, cytokines and growth factors have been postulated as target of the autoimmune process in the dermopathy, the pathogenesis of PTM remains unclear. We hypothesize that the local...
Paper Details
Title
Local immune microenvironment of skin may play an important role in the development of pretibial myxedema
Published Date
Jun 11, 2021
Journal
Volume
30
Issue
12
Pages
1820 - 1824
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