Preclinical autophagy modulatory nanomedicines: big challenges, slow advances
Abstract
Autophagy is a critical housekeeping pathway to remove toxic protein aggregates, damaged organelles, providing cells with bioenergetic substrates needed to survive under adverse conditions. Since altered autophagy is associated with diverse diseases, its pharmacological modulation is considered of therapeutic interest. Nanomedicines may reduce the toxicity and improve the activity of toxic autophagy modulatory drugs (amd).The status of the most...
Paper Details
Title
Preclinical autophagy modulatory nanomedicines: big challenges, slow advances
Published Date
Jun 1, 2021
Volume
18
Issue
10
Pages
1415 - 1434
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