Approaches for refining and furthering the development of CAR-based T cell therapies for solid malignancies
Volume: 16, Issue: 10, Pages: 1105 - 1117
Published: May 26, 2021
Abstract
Introduction: Chimeric antigen receptor-engineered T-cells typically use the binding domains of antibodies to target cytotoxicity toward tumors. This approach has produced great efficacy against selected hematological cancers, but benefit in solid tumors has been limited. Characteristically, the microenvironment in solid tumors restricts CAR T cell function, thereby limiting success. Enhancing efficacy will depend on novel target discovery to...
Paper Details
Title
Approaches for refining and furthering the development of CAR-based T cell therapies for solid malignancies
Published Date
May 26, 2021
Volume
16
Issue
10
Pages
1105 - 1117
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History