Tertiary lymphoid structures correlate with better prognosis in cutaneous angiosarcoma

Cutaneous angiosarcoma (CAS) is a rare malignant sarcoma for which there is no effective treatment. The prognosis is extremely poor, and the development of novel therapies is crucial. In general, soft tissue sarcomas are considered immunologically cold, but immune checkpoint inhibitors (ICIs), including anti-programmed death-1 (PD-1) antibodies, were recently reported to be effective against CAS [ [1] Hofer S. Zeidler K. Schipf A. Kempf W....