POS0447 PHYSICAL FUNCTION IN PATIENTS WITH RA, STRATIFIED BY SEROSTATUS AND TREATMENT LINE, FOLLOWING SC ABATACEPT: POST HOC ANALYSIS OF AN OBSERVATIONAL, 2-YEAR STUDY CONDUCTED IN ROUTINE CLINICAL PRACTICE (ASCORE)

Background: RA is characterised by the production of autoantibodies, including RF and anti-citrullinated protein antibodies (ACPAs). 1 Seropositive disease is associated with poorer prognosis in patients with RA, 2 and response to different treatments has been shown to vary based on ACPA status. 3 ASCORE ( A batacept S ub C utane O us in R outine Clinical Practic E ; NCT02090556 ) was a 2-year, observational, prospective, multicentre study of SC...