Fast and single method for quantitation of ricinine or L-abrine in plasma and urine by ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS)

L-abrine and ricinine are two small molecules found respectively in the seeds of Abrus precatorius and Ricinus communis. L-abrine and ricinine are extracted simultaneously with the toxins ricin and abrin from the seeds and are therefore exposure markers for these toxins. We developed and validated a fast and simple method for the simultaneous quantitation of ricinine and L-abrine in plasma and urine by ultra-high performance liquid...