Glycine Attenuates Citrobacter rodentium‐Induced Colitis by Regulating ATF6‐Mediated Endoplasmic Reticulum Stress in Mice

Inflammatory bowel disease (IBD) is an inflammatory gastrointestinal disorder in which endoplasmic reticulum (ER) stress and dysbiosis of the intestinal microbiota are implicated. Glycine supplementation is reported to reduce inflammatory responses in experimental colitis. However, the underlying mechanisms responsible for the beneficial effects remain unclear.Female C57BL/6 mice are orally administered with glycine (3.5 or 5.2 g kg-1 body...