Hypoxia and Inflammation: Insights From High-Altitude Physiology
Abstract
The key regulators of the transcriptional response to hypoxia and inflammation (hypoxia inducible factor, HIF, and nuclear factor-kappa B, NF-κB, respectively) are evolutionarily conserved and share significant crosstalk. Tissues often experience hypoxia and inflammation concurrently at the site of infection or injury due to fluid retention and immune cell recruitment that ultimately reduces the rate of oxygen delivery to tissues. Inflammation...
Paper Details
Title
Hypoxia and Inflammation: Insights From High-Altitude Physiology
Published Date
May 26, 2021
Journal
Volume
12
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