Can quantitative analysis of multi-parametric MRI independently predict failure of focal salvage HIFU therapy in men with radio-recurrent prostate cancer?

Arnas Rakauskas; Taimur T. Shah; Max Peters; Jagpal S. Randeva; Feargus Hosking-Jervis; Michael J. Schmainda; Clement Orczyck; Mark Emberton; Manit Arya; Caroline M. Moore

doi:https://doi.org/10.1016/j.urolonc.2021.04.017

doi.org/10.1016/j.urolonc.2021.04.017

Can quantitative analysis of multi-parametric MRI independently predict failure of focal salvage HIFU therapy in men with radio-recurrent prostate cancer?

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..., Caroline M. Moore

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Urologic Oncology: Seminars and Original Investigations2.70

Volume: 39, Issue: 12, Pages: 830.e1 - 830.e8

Published: Dec 1, 2021

Abstract

Focal salvage HIFU is a feasible therapeutic option in some men who have recurrence after primary radiotherapy for prostate cancer. We aimed to determine if multi-parametric quantitative parameters, in addition to clinical factors, might have a role in independently predicting focal salvage HIFU outcomes.A retrospective registry analysis included 150 consecutive men who underwent focal salvage HIFU (Sonablate500) (2006-2015); 89 had mpMRI...