Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation
Abstract
CIMP (CpG island methylator phenotype) is an epigenetic molecular subtype, observed in multiple malignancies and associated with the epigenetic silencing of tumor suppressors. Currently, for most cancers including gastric cancer (GC), mechanisms underlying CIMP remain poorly understood. We sought to discover molecular contributors to CIMP in GC, by performing global DNA methylation, gene expression, and proteomics profiling across 14 gastric...
Paper Details
Title
Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation
Published Date
Jun 1, 2021
Journal
Volume
22
Issue
1
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