The protein corona and its effects on nanoparticle-based drug delivery systems
Abstract
In most cases, once nanoparticles (NPs) enter the blood, their surface is covered by biological molecules, especially proteins, forming a so-called protein corona (PC). As a result, what the cells of the body “see” is not the NPs as formulated by the chemists, but the PC. In this way, the PC can influence the effects of the NPs and even mask the desired effects of the NP components. While this can argue for trying to inhibit protein-nanomaterial...
Paper Details
Title
The protein corona and its effects on nanoparticle-based drug delivery systems
Published Date
Jul 1, 2021
Journal
Volume
129
Pages
57 - 72
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