Optimization of Nanoclay/Polyacrylonitrile Scaffold Using Response Surface Method for Bone Differentiation of Human Mesenchymal Stem Cells
Abstract
Response surface methodology (RSM) based on the D-optimal algorithm was employed here for the electrospinning of nanoclay/polyacrylonitrile (PAN) composite scaffold by the aim of obtaining the lower fiber diameter and better mechanical properties for bone regeneration. The input parameters included the electrospinning voltage, flow rate and the ratio of nanoclay/PAN and the obtained values for the optimum point were 17 kV for the applied...
Paper Details
Title
Optimization of Nanoclay/Polyacrylonitrile Scaffold Using Response Surface Method for Bone Differentiation of Human Mesenchymal Stem Cells
Published Date
May 28, 2021
Journal
Volume
67
Issue
10
Pages
1176 - 1185
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