Prospective comparative study: metabolomics profiles of exudate and serum for patients with and without venous ulcer wound itch

Introduction: Itch is an unpleasant sensation that elicits the desire to scratch and can cause great distress, particularly in persons with venous ulcers. This pilot study explored the difference in metabolic profiles for wound exudate and serum in patients with or without venous ulcer wound itch. Methods: Patient information, wound assessment, and itch sensation ratings were recorded. Wound fluid and blood were collected for metabolomics...