Clinical Pharmacology of Antibody-Drug Conjugates
Abstract
Antibody-drug conjugates (ADCs) are biopharmaceutical products where a monoclonal antibody is linked to a biologically active drug (a small molecule) forming a conjugate. Since the approval of first ADC (Gemtuzumab ozogamicin (trade name: Mylotarg)) for the treatment of CD33-positive acute myelogenous leukemia, several ADCs have been developed for the treatment of cancer. The goal of an ADC as a cancer agent is to release the cytotoxic drug to...
Paper Details
Title
Clinical Pharmacology of Antibody-Drug Conjugates
Published Date
May 21, 2021
Journal
Volume
10
Issue
2
Pages
20 - 20
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