Peptide-guided JC polyomavirus-like particles specifically target bladder cancer cells for gene therapy
Abstract
The ultimate goal of gene delivery vectors is to establish specific and effective treatments for human diseases. We previously demonstrated that human JC polyomavirus (JCPyV) virus-like particles (VLPs) can package and deliver exogenous DNA into susceptible cells for gene expression. For tissue-specific targeting in this study, JCPyV VLPs were conjugated with a specific peptide for bladder cancer (SPB) that specifically binds to bladder cancer...
Paper Details
Title
Peptide-guided JC polyomavirus-like particles specifically target bladder cancer cells for gene therapy
Published Date
Jun 4, 2021
Journal
Volume
11
Issue
1
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