APOE gene variants in primary dyslipidemia
Abstract
Apolipoprotein E (apoE) is a major apolipoprotein involved in lipoprotein metabolism. It is a polymorphic protein and different isoforms are associated with variations in lipid and lipoprotein levels and thus cardiovascular risk. The isoform apoE4 is associated with an increase in LDL-cholesterol levels and thus a higher cardiovascular risk compared to apoE3. Whereas, apoE2 is associated with a mild decrease in LDL-cholesterol levels. In the...
Paper Details
Title
APOE gene variants in primary dyslipidemia
Published Date
Jul 1, 2021
Journal
Volume
328
Pages
11 - 22
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