Thrombopoietin, Soluble CD40 Ligand, and Platelet Count During Veno-arterial Extracorporeal Membrane Oxygenation

Thrombocytopenia is common during extracorporeal membrane oxygenation (ECMO), and severe thrombocytopenia occurs in up to 25% of patients.1 A recent systematic review and meta-analysis confirmed that around a quarter of adult ECMO patients develop thrombocytopenia and up to half of patients require platelet transfusion.2 The authors concluded that the mechanisms causing thrombocytopenia are multifactorial and remain poorly understood.2...