Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis
Abstract
To assess whether chronic white matter inflammation in patients with multiple sclerosis (MS) as detected in vivo by paramagnetic rim MRI lesions (PRLs) is associated with higher serum neurofilament light chain (sNfL) levels, a marker of neuroaxonal damage.In 118 patients with MS with no gadolinium-enhancing lesions or recent relapses, we analyzed 3D-submillimeter phase MRI and sNfL levels. Histopathologic evaluation was performed in 25 MS...
Paper Details
Title
Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis
Published Date
Aug 10, 2021
Journal
Volume
97
Issue
6
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