Histologic and genomic features of breast cancers with alterations affecting the SWI/SNF (SMARC) genes
Abstract
The SWI/SNF family of proteins is a multisubunit ATPase complex frequently altered in human cancer. Inactivating mutations in SWI/SNF-related matrix-associated actin-dependent regulator of chromatin (SMARCs) underpin a subset of tumors such as the malignant rhabdoid tumor and small cell carcinoma of the ovary, hypercalcemic type. Here, we investigated the genotypic and phenotypic characteristics of breast cancers harboring somatic genetic...
Paper Details
Title
Histologic and genomic features of breast cancers with alterations affecting the SWI/SNF (SMARC) genes
Published Date
Oct 1, 2021
Journal
Volume
34
Issue
10
Pages
1850 - 1859
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History