Silencing of miR-324-5p alleviates rat spinal cord injury by Sirt1
Abstract
MicroRNAs (miRNAs) are implicated in the pathogenesis of spinal cord injury (SCI) as primary regulators. Previous studies have reported that miR-324-5p is involved in the modulation of neural injury, while the underlying mechanisms of miR-324-5p in SCI remain unclear. In a SCI rat model, miR-324-5p was significantly upregulated in the spinal cord tissues after SCI. Downregulation of miR-324-5p via injection of adeno-associated viruses (AAV)...
Paper Details
Title
Silencing of miR-324-5p alleviates rat spinal cord injury by Sirt1
Published Date
Dec 1, 2021
Journal
Volume
173
Pages
34 - 43
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