A Neonatal Mouse Model for Pressure Overload: Myocardial Response Corresponds to Severity

Volume: 8
Published: May 21, 2021
Abstract
The heart regeneration after apical resection and myocardial infarction in neonatal mice has been studied for years. However, the response of neonatal mouse heart under pressure overload is seldom explored. This study aimed to induce pressure overload in neonatal mice through a transverse aortic constriction (TAC) with different-gauge needles so as to investigate the effect of pressure overload on cardiomyocyte proliferation and hypertrophy in...
Paper Details
Title
A Neonatal Mouse Model for Pressure Overload: Myocardial Response Corresponds to Severity
Published Date
May 21, 2021
Volume
8
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