POS0345 CLINICOGENETIC STUDY OF FIVE NOVEL SUSCEPTIBILITY LOCI FOR TAKAYASU ARTERITIS: SUSCEPTIBILITY LOCI IN THE IL12B AND PTK2B REGION, BUT NOT THE LILRA3, DUSP22, KLHL33 REGIONS, ARE ASSOCIATED WITH VASCULAR DAMAGE IN TAKAYASU ARTERITIS

Background: We have previously identified single nucleotide polymorphism (SNP) rs6871626 in IL12B , rs103294 in LILRA3 , rs17133698 in DUSP22 , rs2322599 in PTK2B , and rs1713450 in KLHL33 as non-HLA susceptibility loci in Takayasu arteritis (TAK) [1, 2]. However, the association of these SNPs with clinical features has scarcely investigated. Objectives: In this study, we aimed to examine how these SNPs contribute to clinical features and...