Autologous stem cell therapy in knee osteoarthritis: a systematic review of randomised controlled trials

Stem cell therapy is increasingly used for knee osteoarthritis (KOA). We aimed to review the evidence of autologous mesenchymal stem cell therapy on pain, function and severity on imaging in KOA.Systematic review of randomised controlled trials (RCTs).RCTs evaluating autologous mesenchymal stem cell (MSC) therapy on patient-reported outcome measures and disease severity.Seven databases were searched until 31 December 2020.Risk of bias was...