The Use of an Organo-Selenium Peptide to Develop New Antimicrobials That Target a Specific Bacteria
Abstract
This study examines the use of a covalently selenium-bonded peptide and phage that binds to the Yersinia pestis F1 antigen for the targeting and killing of E. coli expressing this surface antigen. Using a Ph.D.-12 phage-display library for affinity selection of the phage which would bind the F1 antigen of Y. pestis, a phage displaying a peptide that binds the F1 antigen with high affinity and specificity was identified. Selenium was then...
Paper Details
Title
The Use of an Organo-Selenium Peptide to Develop New Antimicrobials That Target a Specific Bacteria
Published Date
May 21, 2021
Journal
Volume
10
Issue
6
Pages
611 - 611
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