Impact of Neoadjuvant Therapy on Survival Following Margin-Positive Resection for Pancreatic Cancer

A positive microscopic margin (R1) following resection of pancreatic ductal adenocarcinoma (PDAC) can occur in up to 80% of patients and is associated with reduced survival and increased recurrence. Our aim was to characterize the impact of neoadjuvant therapy (NAT) on survival and recurrence in patients with PDAC following an R1 resection. A retrospective analysis of patients with PDAC who underwent pancreatectomy from 2008 to 2017 was...