Neutrophil Extracellular Traps in Dengue Are Mainly Generated NOX-Independently
Abstract
Neutrophil extracellular traps (NETs) are increasingly recognized to play a role in the pathogenesis of viral infections, including dengue. NETs can be formed NADPH oxidase (NOX)-dependently or NOX-independently. NOX-independent NETs can be induced by activated platelets and are very potent in activating the endothelium. Platelet activation with thrombocytopenia and endothelial dysfunction are prominent features of dengue virus infection. We...
Paper Details
Title
Neutrophil Extracellular Traps in Dengue Are Mainly Generated NOX-Independently
Published Date
May 26, 2021
Journal
Volume
12
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