Sequential Bilateral Vision Loss in a Woman With Scalp Tenderness and Jaw Claudication.

Published on Jul 1, 2021in JAMA Neurology13.608
· DOI :10.1001/JAMANEUROL.2021.0757
Aaron R. Kaufman3
Estimated H-index: 3
(UIC: University of Illinois at Chicago),
Peter W. MacIntosh5
Estimated H-index: 5
(UIC: University of Illinois at Chicago),
Brooke T Johnson (UIC: University of Illinois at Chicago)
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Extensive research over the last decades basically failed to identify a common cause of noninfectious inflammatory central nervous system (CNS) demyelinating disease. To a great extent, this may reflect that the group of inflammatory CNS demyelinating disorders likely contains multiple pathogenetically distinct disease entities. Indeed, the greatest success so far in deciphering the pathogenesis of a CNS demyelinating disorder resulted from the discovery of anti-aquaporin (AQP)-4 antibodies (ab)...
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Objective To determine the impact of prior corticosteroid treatment on temporal artery biopsy (TAB) yield to establish the diagnosis of giant cell arteritis (GCA). Methods Retrospective study of a consecutive cohort of 78 patients clinically diagnosed and managed as GCA, who received corticosteroids before TAB. Results Among the 78 patients, TAB was positive in 57 (73%) and negative in 21 (27%). No significant differences in the length of the specimen were found between the positive and negative...
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