Validation of the standardized index of shape tool to analyze DCE-MRI data in the assessment of neo-adjuvant therapy in locally advanced rectal cancer

Standardized index of shape (SIS) tool validation to examine dynamic contrast enhanced–magnetic resonance imaging (DCE-MRI) in preoperative chemo-radiation therapy (pCRT) assessment of locally advanced rectal cancer (LARC) in order to guide the surgeon versus more or less conservative treatment. A total of 194 patients (January 2008–November 2020), with III-IV locally advanced rectal cancer and subjected to pCRT were included. Three expert...