Species-specific deployment of Runx2 isoforms and differential regulation of target genes during avian jaw development and evolution
Abstract
null Developmental regulation of bone formation in the jaw skeleton is essential to species-specific adaptation. The jaws are derived from neural crest mesenchyme (NCM), a progenitor population that directs skeletal patterning by exerting temporal and spatial control over molecular and cellular programs for osteogenesis. One important NCM-mediated gene is Runx2, which is a transcription factor required for osteoblast differentiation. RUNX2...
Paper Details
Title
Species-specific deployment of Runx2 isoforms and differential regulation of target genes during avian jaw development and evolution
Published Date
May 25, 2021
Journal
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