Hepatic oxidative damage and Nrf2 pathway protein changes in rats following long-term manganese exposure.

Volume: 37, Issue: 5, Pages: 251 - 259
Published: May 1, 2021
Abstract
This study investigated hepatic oxidative damage in rats following long-term manganese (Mn) exposure and clarified the underlying mechanisms. Forty-eight rats (SPF, male) were randomly assigned to receive low (10 mg/kg, n = 16) or high doses of Mn (50 mg/kg, n = 16) or sterilized distilled water (control group, n = 16). Rats were euthanized after 12 months, and liver Mn levels and histopathological changes were determined. Serum aspartate...
Paper Details
Title
Hepatic oxidative damage and Nrf2 pathway protein changes in rats following long-term manganese exposure.
Published Date
May 1, 2021
Volume
37
Issue
5
Pages
251 - 259
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