Royal jelly fatty acids bioprofiling using TLC-MS and digital image analysis coupled with chemometrics and non-parametric regression for discovering efficient biomarkers against melanoma

A comprehensive approach of untargeted and targeted fatty acid bioprofiling of different royal jelly commercial and pharmaceutical products based on HPTLC-image analysis and melanoma cytotoxic activity together with chemometric analysis was applied in this study for discovering efficient biomarkers. Principal component analysis based on HPTLC-image analysis fingerprints of fatty acid loading plots were used to determine the chemical markers...