Characterizing the tumor microenvironment of metastatic ovarian cancer by single-cell transcriptomics
Abstract
Understanding the cellular composition of the tumor microenvironment and the interactions of the cells is essential to the development of successful immunotherapies in cancer. We perform single-cell RNA sequencing (scRNA-seq) of 9,885 cells isolated from the omentum in 6 patients with ovarian cancer and identify 9 major cell types, including cancer, stromal, and immune cells. Transcriptional analysis of immune cells stratifies our patient...
Paper Details
Title
Characterizing the tumor microenvironment of metastatic ovarian cancer by single-cell transcriptomics
Published Date
May 1, 2021
Journal
Volume
35
Issue
8
Pages
109165 - 109165
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