A dual cardiomyocyte reporter model derived from human pluripotent stem cells
Abstract
Cardiovascular diseases (CVD) remain the leading cause of death in the USA. Cardiomyocytes (CMs) derived from human pluripotent stem cells (hPSCs) provide a valuable cell source for regenerative therapy, disease modeling, and drug screening. Here, we established a hPSC line integrated with a mCherry fluorescent protein driven by the alpha myosin heavy chain (aMHC) promoter, which could be used to purify CMs based on the aMHC promoter activity in...
Paper Details
Title
A dual cardiomyocyte reporter model derived from human pluripotent stem cells
Published Date
May 29, 2021
Journal
Volume
12
Issue
1
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