Spatially-resolved nanometer-scale measurement of cartilage extracellular matrix mobility

ObjectiveTissues have complex structures, comprised of solid and fluid phases. Improved understanding of interactions between joint fluid and extracellular matrix (ECM) is required in models of cartilage mechanics. X-ray photon correlation spectroscopy (XPCS) directly measures nanometer-scale dynamics and can provide insight into biofluid–biosolid interactions in cartilage. This study applies XPCS to evaluate dynamic interactions between intact...